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Cheesy Mexican Beef & Dorito Casserole — The Ultimate Comfort Dinner

Published: Jun 17, 2025 by info.mealsmell · This post may contain affiliate links ·

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Introduction

This Cheesy Mexican Beef & Dorito Casserole is the perfect crowd-pleaser for busy weeknights, casual get-togethers, or anytime you crave bold, comforting flavors in a simple, satisfying dish. Combining seasoned ground beef, creamy cheese, and that unmistakable crunch of Nacho Cheese Doritos, this casserole delivers a fun twist on classic Tex-Mex favorites. It’s easy to make, ready in under 40 minutes, and guaranteed to bring smiles around the table. Plus, it’s one of those nostalgic dishes that just feels like home.


Pro Tip

For the best texture, don’t crush the Doritos too finely — leave some larger pieces to keep that delicious crunch layer intact after baking.


Serving Suggestions

  • Serve with a fresh, zesty side salad to balance the richness.
  • Pair with guacamole and salsa for extra layers of flavor.
  • Enjoy with a cold cerveza or a lime-spiked sparkling water for a festive touch.

Variations

  • Vegetarian: Swap ground beef for seasoned black beans or lentils.
  • Spicy kick: Add diced jalapeños or a dash of hot sauce to the beef mixture.
  • Cheese swap: Use pepper jack or a blend of cheddar and mozzarella for different cheesy notes.
  • Gluten-free: Use gluten-free taco seasoning and substitute Doritos with a gluten-free chip alternative.

Equipment Needed

  • Large skillet: For browning and cooking the beef evenly.
  • 9x13-inch baking dish: Perfect size for layering and baking the casserole.
  • Mixing spoon: To combine ingredients smoothly.
  • Measuring cups: For precise ingredient amounts.

Tips for Success

  1. Brown the meat thoroughly and drain the fat to avoid greasiness.
  2. Simmer the taco seasoning with water to let the flavors meld before adding other ingredients.
  3. Don’t skip draining the canned corn and Rotel to prevent a soggy casserole.
  4. Spread the Doritos evenly on both the bottom and top for balanced crunch.
  5. Let the casserole rest 5 minutes after baking for easier slicing and serving.

Why You’ll Love This Recipe

This casserole brings together creamy, cheesy, and crunchy textures with zesty taco seasoning for a cozy, irresistible meal. It’s quick to prepare, feeds a crowd, and uses simple pantry staples. Whether for family dinners or casual parties, it’s a recipe that will get requested again and again.


Cheesy Mexican Beef & Dorito Casserole — The Ultimate Comfort Dinner

Recipe Card

Ingredients:

  • 1 lb ground beef
  • 1 packet taco seasoning
  • ½ cup water
  • 1 (10 oz) can Rotel (diced tomatoes & green chilies), drained
  • 1 (15 oz) can corn, drained
  • 1 (10.5 oz) can cream of chicken soup
  • ½ cup sour cream
  • 2 cups shredded Mexican cheese blend
  • 1 (9.75 oz) bag Nacho Cheese Doritos, crushed
  • ¼ cup chopped green onions (optional)

Instructions:

  1. Preheat oven to 350°F (175°C).
  2. In a large skillet, brown ground beef over medium heat until fully cooked. Drain excess grease.
  3. Stir in taco seasoning and water, simmer for 5 minutes until thickened.
  4. Add drained Rotel, corn, cream of chicken soup, sour cream, and 1 cup of shredded cheese. Stir to combine.
  5. Spread half of crushed Doritos evenly on the bottom of a 9x13-inch baking dish.
  6. Pour the beef mixture over the Doritos layer.
  7. Top with remaining crushed Doritos and sprinkle remaining cheese over the top.
  8. Bake uncovered for 20–25 minutes or until cheese is melted and bubbly.
  9. Garnish with chopped green onions if desired. Serve hot.

Nutrition Table (per serving, estimated)

  • Calories: 495 kcal
  • Protein: 28g
  • Carbohydrates: 32g
  • Fat: 29g
  • Fiber: 3g
  • Sugar: 4g
  • Sodium: 860mg

FAQ

Q1: How long can I store leftovers?
Store covered in the fridge for up to 3 days.

Q2: Can I reheat this casserole?
Yes, reheat in the oven at 350°F for 10-15 minutes or in the microwave until warmed through.

Q3: Can I freeze this casserole?
Freeze before baking in an airtight container for up to 2 months. Thaw overnight before baking.

Q4: What if I don’t have cream of chicken soup?
You can substitute with cream of mushroom soup or make a quick homemade white sauce.

Q5: Can I prep this ahead of time?
Yes, assemble the casserole a day ahead, keep covered in the fridge, then bake before serving.

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